Clinical PhD Candidate: Experimental Medicine Initiative
M.D. (Melit) | MRCEM
Arlette graduated from the University of Malta in 2009 with a Doctor of Medicine and Surgery and thereafter undertook a Master of Science in Critical Care at Queen Mary University of London. She received foundation and core training in acute, emergency and critical care in Malta and Dundee, prior to obtaining a National Institute for Health Research Academic Clinical Fellowship in Intensive Care Medicine in London. Arlette has undertaken her academic training in Cambridge, where she commenced research into the functional phenotype of deprimed neutrophils under the mentorship of Dr Charlotte Summers. She is currently embarking on a PhD within the Experimental Medicine Initiative at the University of Cambridge.
- Elucidating the functional phenotype of the deprimed neutrophil
- Investigating differential effects of tumour necrosis factor receptor (TNFR) 1 and 2 in modulating neutrophil activation and neutrophil-pulmonary endothelial interactions in healthy volunteers. This project uses TNFR1 inhibition in oesophagectomy patients as a model for acute respiratory distress syndrome.
Keywords: neutrophils, ARDS, TNFR1, priming, depriming
Publications: see Critical Care Group Publications
- Davide Bastoni, Arlette Vassallo, Maurizio Cecconi, Andrew Rhodes. Remote Ischaemic Conditioning. What we know so far. In: London Critical Care 2015