Clinical PhD Candidate
Gates Cambridge Scholar
BMedSc (Hons) | MBBS (Hons)
Alex completed his medical degree at the University of Western Australia in 2013, before working for two years as a junior doctor at Sir Charles Gairdner Hospital and Albany Health Campus, both in Western Australia. Alex’s interest in medical research developed during an Honours year (supervised by Professor Jane Pillow) investigating neonatal cardio-respiratory physiology as a medical student. He joined the Critical Care Group in October 2015 after successfully attaining a Gates Cambridge Scholarship. Alex is supervised by Professors David Menon and Edwin Chilvers, assisted by Dr Andrew Conway-Morris. After completing his PhD, Alex intends to pursue training in anaesthesia and intensive care medicine.
During his PhD Alex is investigating the role of complement component C5a in driving neutrophil dysfunction in human critical illness. Alex is using a variety of techniques to address this question, including confocal microscopy, flow cytometry and proteomics/phosphoproteomics. His work will utilise whole blood and purified neutrophils from both healthy volunteers and critically ill patients in the Addenbrooke’s John V Farman and Neurosciences/Trauma Critical Care Units.
Keywords: neutophils, sepsis, nosocomial infection, C5a, complement
Publications: see Critical Care Group Publications
- Pedrini MJ, Seewann A, Bennett KA, Wood AJT, James I, Burton J, Marshall BJ, Carroll WM, Kermode AG. Helicobacter pylori infection as a protective factor against multiple sclerosis risk in females. J Neurol Neurosurg Psychiatry. 2015: 86; 6. 603-706.
- Wood AJT, Clugston SC, Rawlins JM, Rea S, Edgar, DW, Wood FM. Burn patients, parents and doctors; are we all in agreement? Burns. 2012; 38 (4); 487-92.
- Wood AJT, et al. Oxygen consumption is not predicted by prematurity or BPD in contemporary infants (Abstract). J Paediatr Child Health. 2012; 48 (Suppl. 1): 33.